Anti-Adenylate Cyclase 10 Antibody
Rabbit polyclonal antibody to Adenylate Cyclase 10 from FabGennix (SAC10-101AP).
|Name:||Anti-Adenylate Cyclase 10 Antibody|
|Description:||Rabbit polyclonal antibody to Adenylate Cyclase 10|
|Applications:||ELISA, IP, WB|
|Dilutions:||DB: 1:10,000; ELISA: 1:10,000; Immunoprecipitation: 1:150; Western Blot: 1:500|
|Reactivity:||Human, Mouse, Gorilla, Rat|
|Immunogen:||Synthetic peptide taken within amino acid region 200-250 on mouse Adenylate Cyclase type 10 protein.|
|Concentration:||0.55-0.75 µg/µl in antibody stabilization buffer|
|Storage:||-20⁰C for long term storage|
|Function:||Catalyzes the formation of the signaling molecule cAMP. May function as sensor that mediates responses to changes in cellular bicarbonate and CO(2) levels (By similarity). Has a critical role in mammalian spermatogenesis by producing the cAMP which regulates cAMP-responsive nuclear factors indispensable for sperm maturation in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization (PubMed:14976244, PubMed:16054031). Involved in ciliary beat regulation (By similarity).|
|Tissue Specificity:||Expressed in testis.|
|Sequence Similarities:||Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.|
|Cellular Location:||Cell membrane. Cytoplasm > Cytoskeleton. Cytoplasm > Perinuclear region. Nucleus. Cell projection > Cilium. Cytoplasm. Mitochondrion.
Distributed to subcellular compartments containing cAMP targets. Found as a plasma membrane-associated protein, protein concentrated in the perinuclear region and protein colocalized with actin or tubulin.
|Synonyms:||3',5'-cyclic AMP synthetase Antibody
Adenylate cyclase 10 (soluble) Antibody
Adenylate cyclase homolog Antibody
AH related protein Antibody
ATP pyrophosphate-lyase Antibody
Germ cell soluble adenylyl cyclase Antibody
hypercalciuria absorptive Antibody
Soluble adenylyl cyclase Antibody
Testicular soluble adenylyl cyclase Antibody
testicular soluble adenylyl cyclase (SAC) Antibody
|Information:||Target information shown above is from the UniProt Consortium.|
Please Note: Anti-Adenylate Cyclase 10 Antibody is for research use only. It is not intended for diagnostic of therapeutic use.