Anti-alpha Fetoprotein Antibody [AFP-01] (Biotin) (A320684)

Anti-alpha Fetoprotein Antibody [AFP-01] (Biotin)

Mouse monoclonal [AFP-01] antibody to alpha Fetoprotein (Biotin).

This antibody reacts with human alpha-Fetoprotein (AFP), a 70 kDa oncofetal antigen. AFP is a major fetal plasma protein, but is not present in healthy adult tissues. Elevated AFP concentrations in adult plasma may be an early marker of hepatocellular carcinoma or teratoblastoma, while high concentrations in amniotic fluid may indicate severe congenital defects of a fetus.

WB, ICC, ELISA, IP

ELISA: This antibody has been tested as the detection antibody in a sandwich ELISA for analysis of human alpha fetoprotein in combination with A85534, WB: 1-2 µg/ml; Non-reducing conditions, IP: Interaction of the antibody with AFP is dependent on the presence of calcium ions (strongly inhibited by chelating agents). Such characteristics of the antibody can be exploited for immunoaffinity purification of APF under mild elution conditions.

Human

Purified alpha Fetoprotein.

Mouse

Monoclonal

IgG1

Biotin

This antibody is conjugated with Biotin LC-NHS ester under optimum conditions. The conjugate is purified by size-exclusion chromatography; removing unconjugated antibody and free Biotin.

1 mg/ml

70 kDa

Liquid

Supplied in Phosphate Buffered Saline, pH 7.4, with 15 mM Sodium Azide.

Shipped at 4°C. Store at 2-8°C. Do not freeze!

Afp, AFPD, alpha 1 Fetoprotein, Alpha fetoglobulin, Alpha fetoprotein precursor, Alpha-1-fetoprotein, Alpha-fetoglobulin, Alpha-fetoprotein, alpha-fetoprotein, Hereditary persistence of, included, FETA, FETA_HUMAN, Hereditary persistence of alpha fetoprotein, HPAFP

This product is for research use only. It is not intended for diagnostic or therapeutic use.