Anti-Anthrax Antibody [7821] (A278827)

Anti-Anthrax Antibody [7821]

Mouse monoclonal [7821] antibody to Anthrax.

This antibody recognises the protective antigen (PA) of Bacillus anthracis, also known as the toxin binding protein, a component, along with edema factor and lethal factor, of the anthrax toxin. Protective antigen binds to the cell surface receptor, Anthrax toxin receptor, also known as tumor endothelial marker 8 and mediates transfer of edema factor and lethal factor to the cytosol where they enzymatically modify a number of substrates impairing cellular function.

ELISA: 1:20 - 1:200

Bacterial

Mouse

Monoclonal

7821

IgG2b

100 µg/ml

Liquid

Supplied in Phosphate Buffered Saline with 0.1% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti anthrax antibody, clone 7821 recognizes the protective antigen (PA) of Bacillus anthracis, also known as the toxin binding protein, a component, along with edema factor and lethal factor, of the anthrax toxin. Protective antigen binds to the cell surface receptor, Anthrax toxin receptor, also known as tumor endothelial marker 8 and mediates transfer of edema factor and lethal factor to the cytosol where they enzymatically modify a number of substrates impairing cellular function (Bradley et al. 2001).