Anti-Arginase 1 Antibody [IHC400] (A86887)

Anti-Arginase 1 Antibody [IHC400]

Recombinant mouse monoclonal (IHC400) antibody to Arginase 1.

ELISA, IHC

Liver

IHC: 1:100 - 1:200.

Human

Arginase 1

Mouse

Monoclonal

IHC400

Store at 2-8°C. Do not freeze.

This antibody is intended for in vitro diagnostic (IVD) use.

Anti-Arginase 1 Antibody is intended for qualified laboratories to qualitatively identify by light microscopy the presence of associated antigens in sections of formalin-fixed, paraffin-embedded tissue sections using IHC test methods.

Use of this antibody is indicated, subsequent to clinical differential diagnoses of diseases, as an aid in the identification and differentiation of hepatocellular carcinoma within the context of antibody panels, the patient’s clinical history and other diagnostic tests evaluated by a qualified pathologist.

Arginase 1, encoded by the ARG1 gene, is a cytosolic metalloenzyme expressed predominantly in hepatocytes which plays a key role in the urea cycle by catalyzing the hydrolysis of arginine to ornithine and urea. Argininemia is an inherited autosomal recessive disorder characterized by a buildup of arginine and ammonia in the blood. Anti-Arginase 1 Antibody is highly specific for hepatocytes, and is therefore a sensitive and specific marker of benign and malignant hepatic tumors.

Concentrated antibody is available in either 100µl or 1ml sizes while prediluted antibody is available in either 7ml or 25ml sizes.

Arginase 1 positive control slides are also available in packs of three.