+44 (0)1223 298875

Anti-ARHGEF7 Antibody (Biotin)

 
Rabbit polyclonal antibody to ARHGEF7 (Biotin) from FabGennix (ARHGEF7-BIOTIN).
Name: Anti-ARHGEF7 Antibody (Biotin)
Description: Rabbit polyclonal antibody to ARHGEF7 (Biotin)
Applications: ELISA, WB
Dilutions: DB: 1:10,000; ELISA: 1:10,000; Western Blot: 1:500
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide taken within amino acid region 595-805 on human ARHGEF7 protein.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Biotin
Concentration: 0.59 µg/µl in antibody stabilization buffer
Storage: -20⁰C for long term storage
Function: Acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions (By similarity). May function as a positive regulator of apoptosis. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons.
Post-Translational Modification: Phosphorylated by PTK2/FAK1; this promotes interaction with RAC1 (By similarity). Phosphorylated on Ser-694 by CaMK1; enhancement of GEF activity and downstream activation of RAC1.
Cellular Location: Cell junction > Focal adhesion. Cell projection > Ruffle. Cytoplasm > Cell cortex. Cell projection > Lamellipodium.

Detected at cell adhesions. A small proportion is detected at focal adhesions.
UniProt: Q14155
Synonyms: ARHG7 Antibody
ARHG7_HUMAN Antibody
ARHGEF 7 Antibody
Beta pix Antibody
Beta-Pix Antibody
betaPix Antibody
betaPix-b Antibody
betaPix-c Antibody
Cool Antibody
COOL-1 Antibody
COOL1 Antibody
DKFZp686C12170 Antibody
DKFZp761K1021 Antibody
KIAA0142 Antibody
KIAA0412 Antibody
mKIAA0142 Antibody
Nbla10314 Antibody
P50 Antibody
P50BP Antibody
p85 Antibody
P85COOL1 Antibody
P85SPR Antibody
PAK interacting exchange factor beta Antibody
PAK-interacting exchange factor beta Antibody
PAK3 Antibody
Pak3bp Antibody
PIX Antibody
PIXB Antibody
Rho guanine nucleotide exchange factor (GEF) 7 Antibody
Rho guanine nucleotide exchange factor (GEF) 7b Antibody
Rho guanine nucleotide exchange factor (GEF7) Antibody
Rho guanine nucleotide exchange factor 7 Antibody
SH3 domain containing proline rich protein Antibody
Information: Target information shown above is from the UniProt Consortium.
Please Note: Anti-ARHGEF7 Antibody (Biotin) is for research use only. It is not intended for diagnostic or therapeutic use.
Antibodies.com | ARHGEF7-BIOTIN
Size Price Quantity
100µg £429

or
Request a quotation
Contact Us Directly
  • call icon + 44 (0)1223 298 875
  • + 44 (0)1223 281 447
  • email icon info@antibodies.com
Product Quality
  • guarantee icon
  • We promise guaranteed product quality
  • and expert customer service.
Lead Time: Currently 5-6 Days
Shipping Information
  • £20 to United Kingdom
  • £35 to Europe