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Anti-B2M Antibody (HRP)

Mouse monoclonal (KT135) antibody to B2M (HRP) from Absea Biotechnology (167201A04H).
Name: Anti-B2M Antibody (HRP)
Description: Mouse monoclonal (KT135) antibody to B2M (HRP).
Applications: sELISA
Reactivity: Human
Immunogen: Purified native human B2M.
Host: Mouse
Clonality: Monoclonal
Clone: KT135
Isotype: IgG1
Conjugate: HRP
Purification: IgG is purified through a Protein A column and labelled with horseradish peroxidase.
Concentration: 1 mg/ml
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline with 0.01% Thimerosal.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation (PubMed:25356553).
Involvement in Disease: Immunodeficiency 43: A disorder characterized by marked reduction in serum concentrations of immunoglobulins and albumin, and hypoproteinemia due to hypercatabolism. Patients may suffer from recurrent respiratory tract infections and severe skin disease.

Amyloidosis 8: A form of hereditary generalized amyloidosis. Clinical features include extensive visceral amyloid deposits, renal amyloidosis resulting in nephrotic syndrome, arterial hypertension, hepatosplenomegaly, cholestasis, petechial skin rash. There is no involvement of the nervous system.
Sequence Similarities: Belongs to the beta-2-microglobulin family.
Post-Translational Modification: Glycation of Ile-21 is observed in long-term hemodialysis patients.
Cellular Location: Secreted. Cell surface.

Detected in serum and urine (PubMed:1336137, PubMed:7554280).
UniProt: P61769
Gene ID: 567
Synonyms: B2MG_HUMAN Antibody
Beta 2 microglobin Antibody
beta 2 Microglobulin Antibody
Beta 2 microglobulin precursor Antibody
Beta chain of mhc class 1 proteins Antibody
Beta chain of MHC class I molecules Antibody
Beta-2-microglobulin form pI 5.3 Antibody
CDABP0092 Antibody
Hdcma22p Antibody
Information: Target information shown above is from the UniProt Consortium.
Sandwich ELISA for purified B2M using KT134 coated plate and HRP conjugated KT135
Please Note: All batches are extensively validated and are guaranteed to work as specified, however, QC data is not necessarily from the current lot on sale.
Description: Mouse monoclonal (D3A2) antibody to beta 2 Microglobulin (HRP).
Application: ELISA
Host: Mouse
Isotype: IgG1
Reactivity: Human

£334





Description: Mouse monoclonal (B2M-01) antibody to beta 2 Microglobulin (HRP).
Application: FC, IP, WB, IHC-P, ICC, ELISA, RIA
Host: Mouse
Isotype: IgG2a
Reactivity: Human

£210





Please Note: Anti-B2M Antibody (HRP) is for research use only. It is not intended for diagnostic or therapeutic use.
Antibodies.com | 167201A04H
Size Price Quantity
100µg £186
200µg £273
1mg £730

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Lead Time: Currently 4-6 Days
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  • £20 to United Kingdom
  • £35 to Europe