Anti-BAP1 Antibody [BAP1/2431] (A250407)

Mouse monoclonal [BAP1/2431] antibody to BAP1 for ELISA.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-BAP1 Antibody [BAP1/2431]
Description
Mouse monoclonal [BAP1/2431] antibody to BAP1.
Specificity
The BAP1 gene belongs to the ubiquitin C-terminal hydrolase subfamily of de-ubiquitination enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germ line mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, Uveal melanoma and cutaneous melanoma.
Applications
ELISA
Reactivity
Human
Immunogen
Recombinant fragment, around amino acids 191-326, of human BAP1 protein. The exact sequence is proprietary.
Host
Mouse
Clonality
Monoclonal
Clone ID
BAP1/2431
Isotype
IgG2c
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
91 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-BAP1 Antibody [BAP1/2431] - BSA and Azide free (A253587).
Synonyms
BAP 1, BAP1_HUMAN, BRCA 1 associated protein 1, BRCA1 associated protein 1, BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase), BRCA1-associated protein 1, Cerebral protein 13, Cerebral protein 6, DKFZp686N04275, FLJ35406, FLJ37180, HUCEP 13, Hucep 6, HUCEP13, Hucep6, KIAA0272, TPDS, Ubiquitin carboxy terminal hydrolase, Ubiquitin carboxyl terminal hydrolase BAP 1, Ubiquitin carboxyl terminal hydrolase BAP1, Ubiquitin carboxyl-terminal hydrolase BAP1, UCHL2
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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