Anti-BCL11A Antibody [PCRP-BCL11A-1G10] (A277750)

Mouse monoclonal [PCRP-BCL11A-1G10] antibody to BCL11A for ELISA, WB, IP, Flow Cytometry and IF.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-BCL11A Antibody [PCRP-BCL11A-1G10]
Description
Mouse monoclonal [PCRP-BCL11A-1G10] antibody to BCL11A.
Specificity
Bcl-11a (CtIP-1, EVI9, B cell chronic lymphocytic leukemia (CLL)/lymphoma 11A) and Bcl-11b (CtIP-2, RIT1, B cell CLL/lymphoma 11B) genes play crucial roles in lymphopoiesis and influence the progression of hematopoietic malignancies. Disruption of the Bcl-11b locus is linked to T cell acute lymphoblastic leukemia, and the loss of heterozygosity in mice results in T cell lymphoma. Bcl-11 proteins are related C2H2 zinc-finger transcription factors that act as transcriptional repressors. Bcl-11b can interact with the metastasis-associated proteins MTA1 and MTA2 through the amino-terminal region. Bcl-11a is essential for postnatal development and normal lymphopoiesis. The Bcl-11a mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with Bcl-6.
Applications
ELISA, WB, IP, Flow Cytometry, IF
Dilutions
WB: 1-2 µg/ml, IP: 1-2µg / 100-500µg proteins, Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml
Reactivity
Human
Cross Reactivity
This antibody is predicted to cross react with Mouse and Rat.
Immunogen
Recombinant full-length human BCLL1A protein.
Host
Mouse
Clonality
Monoclonal
Clone ID
PCRP-BCL11A-1G10
Isotype
IgG2a
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
91.2 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-BCL11A Antibody [PCRP-BCL11A-1G10] - BSA and Azide free (A278338).
Synonyms
2810047E18Rik, B cell CLL/lymphoma 11A (zinc finger protein), B cell CLL/lymphoma 11A (zinc finger protein) isoform 2, B-cell CLL/lymphoma 11A, B-cell lymphoma/leukemia 11A, BC11A_HUMAN, BCL-11A, BCL11A B cell CLL/lymphoma 11A (zinc finger protein) isoform 1, BCL11A L, BCL11A S, BCL11A XL, BCL11a-M, BCL11AL, BCL11AS, BCL11AXL, C2H2 type zinc finger protein, COUP TF interacting protein 1, COUP-TF-interacting protein 1, Ctip1, CTIP1, mouse, homolog of, D930021L15Rik, Ecotropic viral integration site 9, Ecotropic viral integration site 9 homolog, Ecotropic viral integration site 9 protein, Ecotropic viral integration site 9 protein homolog, EVI-9, Evi9, Evi9, mouse, homolog of, FLJ10173, FLJ34997, HBFQTL5, KIAA1809, mKIAA1809, OTTHUMP00000159788, OTTHUMP00000159789, OTTHUMP00000201250, OTTHUMP00000202084, Zinc finger protein 856, ZNF856
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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