Anti-Benzoylecgonine Antibody [BE3] (A279803)

Anti-Benzoylecgonine Antibody [BE3]

Mouse monoclonal [BE3] antibody to Benzoylecgonine.

This antibody recognises benzoylecgonine, a metabolite of benzoylmethylecgonine. Benzoylmethylecgonine is also known as cocaine or coke, an alkaloid extracted from the leaves of the South American coca plant, Erythroxylon coca. Coca leaves are traditionally chewed or sucked, causing a slow absorption and hence a slow onset of action. Cocaine hydrochloride, however, is a white crystalline powder that may be snorted, resulting in very quick absorption and action. It may also be used intravenously or smoked as “crack”. Historically it has had many medicinal uses, including as an analgesic and local anesthetic. Currently, the drug is a controlled substance. Cocaine stimulates the central nervous system, resulting in increased alertness, euphoria and a sense of confidence and physical strength. It can increase blood pressure, heart rate and body temperature and, once the effects are worn off, may result in anxiety, fatigue and depression. In the body cocaine is rapidly converted to metabolites, mainly benzoylecgonine and ecgonine methyl ester, with benzoylecgonine being the main urinary metabolite.

ELISA, Immunoassay

Species Independent

Mouse

Monoclonal

BE3

IgG1

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with <0.1% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Benzoylcgonine antibody, clone BE3 recognizes benzoylecgonine, a metabolite of benzoylmethylecgonine. Benzoylmethylecgonine is also known as cocaine or coke, an alkaloid extracted from the leaves of the South American coca plant, Erythroxylon coca. Coca leaves are traditionally chewed or sucked, causing a slow absorption and hence a slow onset of action. Cocaine hydrochloride, however, is a white crystalline powder that may be snorted, resulting in very quick absorption and action. It may also be used intravenously or smoked as “crack”. Historically it has had many medicinal uses, including as an analgesic and local anesthetic. Currently, the drug is a controlled substance. Cocaine stimulates the central nervous system, resulting in increased alertness, euphoria and a sense of confidence and physical strength. It can increase blood pressure, heart rate and body temperature and, once the effects are worn off, may result in anxiety, fatigue and depression. In the body cocaine is rapidly converted to metabolites, mainly benzoylecgonine and ecgonine methyl ester, with benzoylecgonine being the main urinary metabolite.