Anti-beta NGF Antibody - BSA and Azide free (A283754)

Anti-beta NGF Antibody - BSA and Azide free

Rabbit polyclonal antibody to beta NGF.

This antibody recognises beta-Nerve Growth Factor (beta-NGF), a member of the neurotrophin family of proteins. Beta-NGF plays a crucial role in neuronal cell survival and differentiation. It is also critical for the development and maintenance of the nervous system. Beta-NGF elicits its biological function through the transmembrane recetprs trkA and p75NTR. Upon activation of these receptors by beta-NGF, a multitude of signaling pathways are stimulated including MAPK, PI3K and ERK, that sensitize neurons and stimulate growth of axons and dendrites.

WB, ELISA

ELISA: 0.5 µg/ml - 2.0 µg/ml, WB: 0.1 µg/ml - 0.2 µg/ml

Human

E. coli derived recombinant human beta-NGF.

Rabbit

Polyclonal

IgG

Lyophilized

Reconstitute with 0.1 ml of distilled water.

Supplied in Phosphate Buffered Saline.

Lyophilized: Store at -20°C. Reconstituted: Store undiluted at -20°C, avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.

Rabbit anti Human beta-NGF antibody, recognizes beta-Nerve Growth Factor (beta-NGF), a member of the neurotrophin family of proteins. Beta-NGF plays a crucial role in neuronal cell survival and differentiation. It is also critical for the development and maintenance of the nervous system (Yue et al. 2013). Beta-NGF elicits its biological function through the transmembrane recetprs trkA and p75NTR. Upon activation of these receptors by beta-NGF, a multitude of signaling pathways are stimulated including MAPK, PI3K and ERK, that sensitize neurons and stimulate growth of axons and dendrites (Huang et al. 2018).