This antibody recognizes human blood group A including weak variants A₃, A_X, A₃B, A_XB. The specifity of this antibody was confirmed by comparison of specifity and reactivity to standard reagent using >5.000 samples of blood.

Applications

AGG

Reactivity

Human

Immunogen

Mixture of erythrocytes of group A1 and glycoprotein fraction isolated from saliva of secretors with blood group A.

Host

Mouse

Clonality

Monoclonal

Clone ID

HE-195

Isotype

IgM

Conjugate

Unconjugated

Purification

Concentrated by membrane ultrafiltration.

Purity

Tissue culture supernatant.

Product Form

Liquid

Formulation

Supplied as an aliquot of concentrated tissue culture supernatant.

Storage

Shipped at 4°C. Store at 2-8°C. Do not freeze!

Isotype Controls

Mouse IgM [PRF-03] (A86761)

Suitable Secondaries

See all Anti-Mouse IgG Secondaries →

Disclaimer

This product is for research use only. It is not intended for diagnostic or therapeutic use.

Citations for this Clone (1)

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Murine monoclonal antibodies to human A erythrocytes: differential reactivity with N-acetyl-D-galactosamine.

References: Anti-Blood Group A Antigen Antibody [HE-195] (ab2522)

Abstract:

Six different hybridoma cell lines were obtained producing IgM monoclonal antibodies (MAbs) against human blood group A antigen. All these MAbs agglutinate the A1, A1B and A2 erythrocytes, while only one of them agglutinates the A2B erythrocytes. The agglutination activity of 3 of these MAbs is inhibited by N-acetyl-D-galactosamine (D-GalNAc). Dissociation constants of complexes of these MAbs with D-GalNAc are approximately 2.2 X 10(-3) mol/l.

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