Anti-C3a Antibody [H13] (A280536)

Anti-C3a Antibody [H13]

Mouse monoclonal [H13] antibody to C3a.

This antibody recognises human C3a anaphylatoxin, a cleavage product of human complement component C3. C3a increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.recognises a C3a-determinant also present on native C3. Mouse anti Human C3a antibody, clone H13 allows discrimination of ubiquitous or non-specifically bound native C3 or C3a from biologically active C3b fragment, neither C3b or C5 components are recognized by Mouse anti Human C3a antibody, clone H13. Mouse anti Human C3a antibody, clone H13 is reported to block C3a functional activity.

ELISA, WB, IHC-Fr

IHC-Fr: 1:10

Human, Guinea Pig, Rabbit

Human complement component C3.

Mouse

Monoclonal

H13

IgG2b

50 µg/ml after reconstitution.

Lyophilized

Reconstitute with 1 ml of distilled water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Gently mix after reconstitution.

Supplied in Phosphate Buffered Saline with 0.2% BSA and 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Human C3a antibody, clone H13 recognizes human C3a anaphylatoxin, a cleavage product of human complement component C3. C3a increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.Mouse anti Human C3a antibody, clone H13 recognizes a C3a-determinant also present on native C3. Mouse anti Human C3a antibody, clone H13 allows discrimination of ubiquitous or non-specifically bound native C3 or C3a from biologically active C3b fragment, neither C3b or C5 components are recognized by Mouse anti Human C3a antibody, clone H13 (Burger et al. 1987).Mouse anti Human C3a antibody, clone H13 is reported to block C3a functional activity (Hartmann et al. 1997).