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Anti-C9orf72 Antibody (Biotin)

Rabbit polyclonal antibody to C9orf72 (Biotin) from FabGennix (C9ORF72-BIOTIN).
Name: Anti-C9orf72 Antibody (Biotin)
Description: Rabbit polyclonal antibody to C9orf72 (Biotin)
Applications: DB, ELISA, IP, WB
Dilutions: DB: 1:4,000; DB: 1:4,000; ELISA: 1:4,000; Immunoprecipitation: 1:150; Western Blot: 1:500
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide taken within amino acid region 100-200 on human C9orf72 isoform a protein.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Biotin
Concentration: 0.68-0.70 µg/µl in antibody stabilization buffer
Storage: -20⁰C for long term storage

Function: May play a role in endosomal trafficking and autophagy.
Tissue Specificity: Both isoforms are widely expressed, including kidney, lung, liver, heart, testis and several brain regions, such as cerebellum. Also expressed in the frontal cortex and in lymphoblasts (at protein level).
Involvement in Disease: Frontotemporal dementia and/or amyotrophic lateral sclerosis 1: An autosomal dominant neurodegenerative disorder characterized by adult onset of frontotemporal dementia and/or amyotrophic lateral sclerosis in an affected individual. There is high intrafamilial variation. Frontotemporal dementia is characterized by frontal and temporal lobe atrophy associated with neuronal loss, gliosis, and dementia. Patients exhibit progressive changes in social, behavioral, and/or language function. Amyotrophic lateral sclerosis is characterized by the death of motor neurons in the brain, brainstem, and spinal cord, resulting in fatal paralysis.
Cellular Location: Nucleus. Cytoplasm. Endosome. Lysosome. Cytoplasmic vesicle > Autophagosome. Secreted.

Detected in the cytoplasm of neurons from post mortem brain tissue (PubMed:21944778). Detected in the nucleus in fibroblasts (PubMed:21944779).
UniProt: Q96LT7
Synonyms: ALSFTD Antibody
chromosome 9 open reading frame 72 Antibody
CI072_HUMAN Antibody
FTDALS Antibody
MGC23980 Antibody
Protein C9orf72 Antibody
RP11-27J8.2 Antibody
Uncharacterized protein C9orf72 Antibody
Information: Target information shown above is from the UniProt Consortium.

Please Note: Anti-C9orf72 Antibody (Biotin) is for research use only. It is not intended for diagnostic of therapeutic use.
Antibodies.com | C9ORF72-BIOTIN
Size Price Quantity
100µg £429

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