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Anti-PD-L1 Aptamer [Clon-3] (Biotin) (A321153)

Secondary Structure - Anti-PD-L1 Aptamer [Clon-3] (Biotin) (A321153) - Antibodies.com
$800
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Shipping Information

$40
Dispatched from St. Louis, MO.
Lead Time: 20-35 business days.

  • Specifications

Name
Anti-PD-L1 Aptamer [Clon-3] (Biotin)
Description
Synthetic DNA aptamer to PD-L1 [Clon-3] (Biotin).
Aptamer ID
Clon-3
Conjugate

Biotin

Aptamer Resuspension
Resuspend to 100µM with 10mM Tris-HCl, pH 7.5, and 0.1mM EDTA.
Apatmer Binding Conditions
Binding Buffer: 50mM HEPES Buffer, pH 7.5, with 100mM Sodium Chloride, 1mM Magnesium Chloride, 5mM Potassium Chloride, and 1mM Calcium Chloride. Binding/Wash Buffer (Capture SELEX): 10mM Tris-HCl Buffer, pH 7.4, with 1mM EDTA and 1M Sodium Chloride. Binding Temperature: 37°C.
Sequence
5'-dCpdCpdCpdTpdCpdCpdTpdCpdCpdTpdApdApdCpdTpdGpdTpdTpdCpdCpdTpdApdCpdGpdApdApdApdCpdGpdApdGpdCpdTpdTpdApdTpdGpdCpdGpdTpdApdApdTpdGpdApdTpdGpdApdCpdTpdGpdTpdCpdGpdTpdApdGpdTpdTpdCpdGp-3'
Aptamer Length
60 nt
Aptamer Molecular Weight (Da)
18,462 Da
Aptamer Affinity
Affinity (Kd) = 70.1±14.2 nM nM
Extinction Coefficient
640.4 M-1cm-1
Purification
HPLC
Product Form
Lyophilized
Concentration
Reconstitution dependent.
Formulation
Lyophilized from nuclease-free water (no residual salts).
Storage
Shipped at 4°C. Lyophilized: Store at -20°C. Reconstituted: Store short term at 4°C (i.e. use within days) or aliquot and store at -20°C (medium term: i.e. use within weeks) or -80°C long term. Avoid freeze/thaw cycles.
Product Notes
Anti-PD-L1 Aptamer [Clon-3] (Biotin) (A321153) is a replica of the aptamer described in PMID: 33724284.
General Notes
Aptamers have not been validated by Antibodies.com and they need to be tested/evaluated under identical conditions to which they were reported in the literature including, but not limited to, temperature and matrix/buffer conditions. All aptamers are manufactured on request and have a lead time of 20-35 business days.
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.

  • Scientific Validation DataValidation Data (1)

Secondary Structure - Anti-PD-L1 Aptamer [Clon-3] (Biotin) (A321153) - Antibodies.comEnlarge Image

Anti-PD-L1 Aptamer [Clon-3] (Biotin) (A321153)

Secondary structure of Anti-PD-L1 Aptamer [Clon-3] (Biotin) (A321153), with a dG of -2.34 kcal/mol.
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