Cyanine 3 tetrazine (A270148)

Cyanine 3 tetrazine

Cyanine 3 tetrazine is a fluorescent dye with tetrazine moiety for a conjugation reaction called TCO (trans-cyclooctene) ligation. Actually, tetrazines react not only with trans-cyclooctenes, but also with (methyl)cyclopropenes and strained non-benzo-fused cycloalkynes. Cyanine 3 is a moderately hydrophobic dye, enabling labeling in non-aqueous environment as well as in aqueous media containing some organic co-solvent like acetonitrile or DMSO. For reactions in purely aqueous media, a sulfonated version of this reagent is available.

555 nm

150000 M^-1cm^-1

570 nm

0.31

0.04

611.4

95% (by ¹H NMR and HPLC-MS).

C₄₀H₄₆N₇BF₄O

727.64 kDa

Dark red solid.

Good in DCM, DMSO, and DMF.

Shipped at room temperature. Upon delivery, store in the dark at -20°C. Avoid prolonged exposure to light. Desiccate.

This product is for research use only. It is not intended for diagnostic or therapeutic use.