Anti-5HT7 Receptor Antibody (A283107)

Anti-5HT7 Receptor Antibody

Rabbit polyclonal antibody to 5HT7 Receptor.

This antibody recognises the C-terminal region of the serotonin (5-hydroxytryptamine, 5-HT) receptor 5-HT7.

IHC-P 1: 10 µg/ml

Human, Mouse

Synthetic peptide corresponding to the C-terminus of human 5-HT7 receptor, conjugated to Keyhole Limpet Haemocyanin.

Rabbit

Polyclonal

IgG

Liquid

Supplied in Phosphate Buffered Saline with 0.1% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

5HT7 Receptor belongs to the G-protein coupled receptor superfamily. Serotonin is a neurotransmitter and vasoactive amine which is thought to play a role in various cognitive and behavioural functions including pain, appetite, mood and sleep.Signalling through 5-HT7 has several effects, including regulation of the circadian rhythm and mediation of smooth-muscle relaxation in the vasculature and gastrointestinal tract. Signalling though 5-HT7 has also been shown to contribute to early T-cell activation.5-HT7 has been implicated in depression, autism, and other neuropsychiatric disorders.

5-HT-7, 5-HT-X, 5-HT7, 5-hydroxytryptamine receptor 7, HTR7, Serotonin receptor 7