This antibody recognises human Activating molecule in beclin-1-regulated autophagy (AMBRA1), also known as WDR94.AMBRA1 is involved in the regulation of autophagy. Research indicates that it controls protein turnover during neuronal development and in regulating normal cell survival and proliferation.At least 5 isoforms of AMBRA have been identified.
Applications
WB, IHC-P, IF
Dilutions
IF: 20 µg/ml, IHC-P: 5 µg/ml, WB: 1 - 2 µg/ml
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide corresponding to 15 amino acids near the C-terminus of human AMBRA1.
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugate
Unconjugated
Concentration
1 mg/ml
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 0.02% Sodium Azide.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
General Notes
Rabbit anti AMBRA1 (C-Terminal) antibody recognizes human Activating molecule in beclin-1-regulated autophagy (AMBRA1), also known as WDR94.AMBRA1 is involved in the regulation of autophagy. Research indicates that it controls protein turnover during neuronal development and in regulating normal cell survival and proliferation.At least 5 isoforms of AMBRA have been identified.
Synonyms
Activating molecule in BECN1-regulated autophagy protein 1, DCAF3, DDB1- and CUL4-associated factor 3, KIAA1736
