Mouse monoclonal [AB03/2F11] antibody to AMPK beta 2 / PRKAB2.
Specificity
This antibody recognises 5'-AMP-activated protein kinase subunit beta-2, also known as PRKAB2.AMPK BETA 2 is part of the serine/threonine kinase family and is expressed in the liver and skeletal muscle. AMPK has been seen to inhibit cellular proliferation and in turn act as a tumor suppressor. This has particularly been seen in liver, lung and colorectal cancer.
Applications
WB
Dilutions
WB: 1:1,000 - 1:2,000
Reactivity
Human
Immunogen
E. coli derived recombinant protein corresponding to amino acids 1-272 of human AMPK Beta 2.
Protein G affinity chromatography of tissue culture supernatant.
Concentration
1 mg/ml
Molecular Weight
Approximately 32 kDa in HepG2 cell lysates.
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
General Notes
Mouse anti human AMPK BETA 2 antibody, clone AB03/2F11 recognizes 5'-AMP-activated protein kinase subunit beta-2, also known as PRKAB2.AMPK BETA 2 is part of the serine/threonine kinase family and is expressed in the liver and skeletal muscle. AMPK has been seen to inhibit cellular proliferation and in turn act as a tumor suppressor. This has particularly been seen in liver, lung and colorectal cancer (Li et al. 2015).
