This antibody recognises the beta amyloid (1-42) peptide, the main constituent of amyloid plaques in the brains of Alzheimer's disease patients. Similar plaques appear in some variants of Lewy body dementia and in inclusion body myositis, a muscle disease. Beta amyloid also forms aggregates coating cerebral blood vessels in cerebral amyloid angiopathy. Rabbit anti Human beta amyloid antibody (AHP677) may be used in immunohistochemical staining of Alzheimer's disease plaques.
Applications
WB, IHC-P, ELISA, IHC-Fr
Dilutions
WB: 1:500 - 1:1,000
Reactivity
Human
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugate
Unconjugated
Concentration
Lot Specific
Purity
Serum.
Product Form
Liquid
Formulation
Supplied as serum with <0.1% Sodium Azide.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
General Notes
Rabbit anti Human beta amyloid antibody recognizes the beta amyloid (1-42) peptide, the main constituent of amyloid plaques in the brains of Alzheimer's disease patients. Similar plaques appear in some variants of Lewy body dementia and in inclusion body myositis, a muscle disease (Benveniste et al. 2015). Beta amyloid also forms aggregates coating cerebral blood vessels in cerebral amyloid angiopathy (Kirshner et al. 2015).Rabbit anti Human beta amyloid antibody (AHP677) may be used in immunohistochemical staining of Alzheimer's disease plaques.
