Anti-Angiotensin I Antibody [Ang E9 (BGN/KA/4H)] (A279678)

Anti-Angiotensin I Antibody [Ang E9 (BGN/KA/4H)]

Mouse monoclonal [Ang E9 (BGN/KA/4H)] antibody to Angiotensin I.

This antibody recognises Angiotensin I and does not react with angiotensin II, III or angiotensinogen in ELISA. Angiotensin I is important in the Renin-Angiotensin-Aldosterone System (RAAS). RAAS is responsible for the regulation of blood pressure and water retention in the body. Angiotensin I is produced from a reaction between the renal enzyme Renin and angiotensinogen. It is converted by Angiotensin Converting Enzyme (ACE) into a vasoactive form called Angiotensin II which is responsible for increasing blood pressure.

In a simple indirect ELISA, using 1 µg of Angiotensin I coated per well, the 50% binding was observed at an antibody dilution of 1:12K. Under the same conditions, the end point titre was observed at an antibody dilution of 1:100K.

Human

Synthetic peptide sequence PFHLVIHNES(C) corresponding to amino acids 40-49 of the angiotensinogen precursor conjugated to HMW carrier protein.

PFHLVIHNES(C)

Mouse

Monoclonal

Ang E9 (BGN/KA/4H)

Protein G affinity chromatography of ascites.

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with <0.1% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Human Angiotensin I, clone Ang E9, is specific for Angiotensin I and does not react with angiotensin II, III or angiotensinogen in ELISA. Angiotensin I is important in the Renin-Angiotensin-Aldosterone System (RAAS). RAAS is responsible for the regulation of blood pressure and water retention in the body. Angiotensin I is produced from a reaction between the renal enzyme Renin and angiotensinogen. It is converted by Angiotensin Converting Enzyme (ACE) into a vasoactive form called Angiotensin II which is responsible for increasing blood pressure.