This antibody recognises the human Apolipoprotein H molecule, also known as beta 2 glycoprotein 1, APC inhibitor, activated protein C-binding protein or anticardiolipin cofactor. Apolipoprotein H is expressed by placental trophoblast cells at high levels. Although the normal physiological role is not known, the protein appears to act as a co-factor for the binding of autoantibodies to phospholipids to trophoblasts, a process involved in the pathogenesis of recurrent miscarriage and thrombotic tendencies due to antiphospholipid syndrome.
Applications
WB, IHC-Fr
Reactivity
Human
Host
Mouse
Clonality
Monoclonal
Clone ID
ID2
Isotype
IgG1
Conjugate
Unconjugated
Concentration
Lot Specific
Purity
Tissue Culture Supernatant
Product Form
Liquid
Formulation
Supplied in <0.1% Sodium Azide.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
General Notes
Mouse anti Human apolipoprotein H antibody, clone ID2 recognizes the human Apolipoprotein H molecule, also known as beta 2 glycoprotein 1, APC inhibitor, activated protein C-binding protein or anticardiolipin cofactor. Apolipoprotein H is expressed by placental trophoblast cells at high levels. Although the normal physiological role is not known, the protein appears to act as a co-factor for the binding of autoantibodies to phospholipids to trophoblasts, a process involved in the pathogenesis of recurrent miscarriage and thrombotic tendencies due to antiphospholipid syndrome.
Synonyms
Activated protein C-binding protein, Anticardiolipin cofactor, APC inhibitor, Apolipoprotein H, B2G1, B2GPI, Beta(2)GPI, Beta-2-glycoprotein 1, Beta-2-glycoprotein I