Anti-ATG16L1 Antibody (A283261)

Anti-ATG16L1 Antibody

Rabbit polyclonal antibody to ATG16L1.

This antibody recognises human Autophagy-related protein 16 (ATG16). ATG16 is a member of the autophagy protein family and forms a complex with the ATG5-ATG12 conjugate. This multimeric protein has been shown to be essential for autophagosome formation in both yeast and mammals and targets the ATG5-ATG12 complex to the autophagic isolation membrane during the formation of the autophagosome. Because mammalian ATG16 has seven WD-repeats in its C-terminal domain, it has been suggested that these may form a platform for further protein-protein interactions.Multiple isoforms of ATG16 exist.

WB, IHC-Fr

WB: 0.25 - 0.5 µg/ml

Human, Mouse, Rat

Synthetic peptide corresponding to 18 amino acids from near the centre of human ATG16.

Rabbit

Polyclonal

IgG

Approximately 75 kDa in HeLa cell lysate.

Liquid

Supplied in Phosphate Buffered Saline with 0.02% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Rabbit anti ATG16 (Internal Region) antibody recognizes human Autophagy-related protein 16 (ATG16). ATG16 is a member of the autophagy protein family and forms a complex with the ATG5-ATG12 conjugate. This multimeric protein has been shown to be essential for autophagosome formation in both yeast and mammals and targets the ATG5-ATG12 complex to the autophagic isolation membrane during the formation of the autophagosome. Because mammalian ATG16 has seven WD-repeats in its C-Terminal domain, it has been suggested that these may form a platform for further protein-protein interactions.Multiple isoforms of ATG16 exist.

APG16-like 1, APG16L, Autophagy-related protein 16-1