Anti-ATM (pSer1981) Antibody (A283557)

Anti-ATM (pSer1981) Antibody

Rabbit anti ATM (pSer1981)

Rabbit anti ATM (pSer1981) antibody recognizes serine-protein kinase ATM, also known as ataxia telangiectasia mutated, when phosphorylated at serine 1981. ATM is a serine/threonine protein kinase and a member of the PI3K/P14K-kinase family. ATM is a cell cycle checkpoint kinase that exists as an inactive dimer. In response to DNA damage, autophosphorylation of ATM at serine 1981 occurs, resulting in the dissociation of the dimer and initiating ATM kinase activity (Bakkenist and Kastan 2003).

WB, IHC-P

Human

Phospho specific-peptide corresponding to residues surrounding serine 1981 of human ATM.

Rabbit

Polyclonal

Affinity chromatography.

Liquid

Supplied in Phosphate Buffered Saline with 50% Glycerol and 0.02% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.