This antibody recognises SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1.SMARCE1 forms part of the ATP-dependent chromatin remodeling complex SWI/SNF, required for transcriptional activation of genes normally inhibited by chromatin. Mutations in the genes encoding members of this complex, including SMARCE1, have been observed in a variety of cancers.
Applications
WB
Dilutions
WB: 1:500 - 1:2,000
Reactivity
Human
Immunogen
A peptide derived from within the C-terminus of human SMARCE1.
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugate
Unconjugated
Concentration
Lot Specific
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 0.035% Sodium Azide and 30% Glycerol.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
General Notes
Rabbit anti Human SMARCE1 antibody recognizes SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1.SMARCE1 forms part of the ATP-dependent chromatin remodeling complex SWI/SNF, required for transcriptional activation of genes normally inhibited by chromatin. Mutations in the genes encoding members of this complex, including SMARCE1, have been observed in a variety of cancers (Biegel et al. 2014).
