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Anti-BCL11A Antibody [PCRP-BCL11A-1G10] (A277750)

Mouse monoclonal [PCRP-BCL11A-1G10] antibody to BCL11A for ELISA, WB, IP, Flow Cytometry and IF.

Alternative Formats and ConjugatesAlternative Formats

Shipping Information

$40
Dispatched from St. Louis, MO.
Lead Time: 5-8 business days.
Name
Anti-BCL11A Antibody [PCRP-BCL11A-1G10]
Description
Mouse monoclonal [PCRP-BCL11A-1G10] antibody to BCL11A.
Specificity
Bcl-11a (CtIP-1, EVI9, B cell chronic lymphocytic leukemia (CLL)/lymphoma 11A) and Bcl-11b (CtIP-2, RIT1, B cell CLL/lymphoma 11B) genes play crucial roles in lymphopoiesis and influence the progression of hematopoietic malignancies. Disruption of the Bcl-11b locus is linked to T cell acute lymphoblastic leukemia, and the loss of heterozygosity in mice results in T cell lymphoma. Bcl-11 proteins are related C2H2 zinc-finger transcription factors that act as transcriptional repressors. Bcl-11b can interact with the metastasis-associated proteins MTA1 and MTA2 through the amino-terminal region. Bcl-11a is essential for postnatal development and normal lymphopoiesis. The Bcl-11a mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with Bcl-6.
Applications
ELISA, WB, IP, Flow Cytometry, IF
Dilutions
WB: 1-2 µg/ml, IP: 1-2µg / 100-500µg proteins, Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml
Reactivity
Human
Cross Reactivity
This antibody is predicted to cross react with Mouse and Rat.
Immunogen
Recombinant full-length human BCLL1A protein.
Host
Mouse
Clonality
Monoclonal
Clone ID
PCRP-BCL11A-1G10
Isotype
IgG2a
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
91.2 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-BCL11A Antibody [PCRP-BCL11A-1G10] - BSA and Azide free (A278338).
Synonyms
B-cell CLL/lymphoma 11A, B-cell lymphoma/leukemia 11A, BCL-11A, COUP-TF-interacting protein 1, CTIP1, Ecotropic viral integration site 9 protein homolog, EVI-9, EVI9, KIAA1809, Zinc finger protein 856, ZNF856
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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Proteins predicted to interact with BCL11A

Predicted protein interactions based upon String database. Revelancy score correlates with probability of interaction.
99.1% Relevancy Score
98.9% Relevancy Score
97.5% Relevancy Score
97.4% Relevancy Score
97% Relevancy Score
96.7% Relevancy Score
96.5% Relevancy Score
96.2% Relevancy Score
95.7% Relevancy Score