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Anti-Blood Group Kell Antigen Antibody [BRIC203] (A279857)

This product is discontinued

Anti-Blood Group Kell Antigen Antibody [BRIC203] (A279857) has been discontinued and is no longer available.

View all Blood Group Kell Antigen Antibodies.

Name
Anti-Blood Group Kell Antigen Antibody [BRIC203]
Description
Mouse monoclonal [BRIC203] antibody to Blood Group Kell Antigen.
Specificity
This antibody recognises human CD238, also known as the kell blood group antigen Kpbc. The kell blood group antigens are carried on the ~93 kDa erythrocyte membrane glycoprotein.In hemagglutination tests, Mouse anti Human CD238 antibody, clone BRIC203 reacts with Kp (a-b+) but not Kp (a+b-). In addition Mouse anti Human CD238 antibody, clone BRIC203 will agglutinate Kp (a+b-c+) and Kp (a-b-c+) erythrocytes but not react with Ko erythrocytes. Weaker staining in flow cytometry is observed on erythroblasts derived from CD34+ hematopoietic progenitor cells, compared to Kp (a-b+) red blood cells.
Applications
Flow Cytometry, IP, Haemagglutination
Dilutions
Use 10µl of the suggested working dilution to label 106 cells in 100µl
Reactivity
Human
Immunogen
Human erythrocytes.
Host
Mouse
Clonality
Monoclonal
Clone ID
BRIC203
Isotype
IgG1
Conjugate

Unconjugated

Purification
Protein G affinity chromatography of tissue culture supernatant.
Concentration
1 mg/ml
Product Form
Liquid
Formulation
Supplied in TRIS Buffered Saline with <0.1% Sodium Azide and =100mM glycine.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
General Notes
Mouse anti Human CD238 antibody, clone BRIC203 recognizes human CD238, also known as the kell blood group antigen Kpbc. The kell blood group antigens are carried on the ~93 kDa erythrocyte membrane glycoprotein.In hemagglutination tests, Mouse anti Human CD238 antibody, clone BRIC203 reacts with Kp (a-b+) but not Kp (a+b-). In addition Mouse anti Human CD238 antibody, clone BRIC203 will agglutinate Kp (a+b-c+) and Kp (a-b-c+) erythrocytes but not react with Ko erythrocytes. Weaker staining in flow cytometry is observed on erythroblasts derived from CD34+ hematopoietic progenitor cells, compared to Kp (a-b+) red blood cells.
Synonyms
CD238, KEL, Kell blood group glycoprotein
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.

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