Anti-C3b Antibody [H11] (A280535)

Anti-C3b Antibody [H11]

Mouse monoclonal [H11] antibody to C3b.

This antibody recognises human C3b, part of the complement system. C3 is cleaved by C3-convertase creating C3a and C3b, which binds to the surface of pathogens leading to their destruction by phagocytic cells. recognises a determinant present on native (circulating) C3 and on the fragments C3b and C3c. The antibody is directed to a determinant present on the betachain of the C3 molecule (Western blot). It does not react with the anaphylatoxin C3a or the fragment C3d and does not inhibit the haemolytic function of C3.

WB, IHC-Fr

IHC-Fr: 1:10

Human

Human C3b.

Mouse

Monoclonal

H11

IgG1

50 µg/ml after reconstitution.

Lyophilized

Reconstitute with 1 ml of distilled water. Care should be taken during reconstitution as the antibody may appear as a film at the bottom of the vial. Gently mix after reconstitution.

Supplied in Phosphate Buffered Saline with 0.2% BSA and 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Human C3b antibody, clone H11 recognizes human C3b, part of the complement system. C3 is cleaved by C3-convertase creating C3a and C3b, which binds to the surface of pathogens leading to their destruction by phagocytic cells. Mouse anti Human C3b antibody, clone H11 recognizes a determinant present on native (circulating) C3 and on the fragments C3b and C3c. The antibody is directed to a determinant present on the betachain of the C3 molecule (Western blot). It does not react with the anaphylatoxin C3a or the fragment C3d and does not inhibit the haemolytic function of C3.