Anti-Canine Heartworm Antibody [HW1-39] (A280669)

Anti-Canine Heartworm Antibody [HW1-39]

Mouse monoclonal [HW1-39] antibody to Canine Heartworm.

This antibody recognises both male and female ether extracted parasite antigen of canine heartworm.Canine heartworm infection, caused by the filarial nematode Dirofilaria immitis, is an insidious and potentially fatal condition transmitted by mosquitoes, which primarily affects the heart and lungs of dogs, but may also affect other species including cats, foxes, sea-lions, ferrets and humans.Canine heartworm disease, resulting ultimately in damage to the pulmonary vasculature system, is largely attributed to the immunological response of the host to the presence of the adult parasites, and in many cases their microscopic offspring (microfilaria) which circulate in the bloodstream, but growing evidence suggests the involvement of further factors/mediators.

WB, ELISA

Invertebrate

Mouse

Monoclonal

HW1-39

IgG1

Protein A affinity chromatography of tissue culture supernatant.

Approximately 170, 155, 98, 80, 70 and 62 kDa under reducing conditions.

Liquid

Supplied in Phosphate Buffered Saline with <0.1% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Canine Heartworm antibody, clone HW1-39 recognizes both male and female ether extracted parasite antigen of canine heartworm.Canine heartworm infection, caused by the filarial nematode Dirofilaria immitis, is an insidious and potentially fatal condition transmitted by mosquitoes, which primarily affects the heart and lungs of dogs, but may also affect other species including cats, foxes, sea-lions, ferrets and humans.Canine heartworm disease, resulting ultimately in damage to the pulmonary vasculature system, is largely attributed to the immunological response of the host to the presence of the adult parasites, and in many cases their microscopic offspring (microfilaria) which circulate in the bloodstream, but growing evidence suggests the involvement of further factors/mediators.