Anti-Caspase-9 (Active) Antibody (A283332)

Anti-Caspase-9 (Active) Antibody

Rabbit anti Caspase-9 (Active)

Rabbit anti caspase-9 antibody recognizes caspase-9 also known as apoptotic protease-activating factor 3 (APAF-3). Caspase-9 as the name implies is a member of the cysteine-aspartic acid protease family.The active form of caspase-9 is generated via cleavage of the pro-caspase-9 protein into two fragments, known as the large and the small fragment. The trigger for caspase-9 cleavage is the binding of cytochrome c to pro-caspase-9, which is released upon receiving apoptotic stimuli.Caspase-9 is an effector caspase that plays a role in the mediation of mitochondrial apoptosis. Active caspase-9 cleaves pro-caspases 3 and 7 into their active forms. Caspase activity can be inhibited by c-IAP1, c-IAP2,XIAP and other members of the inhibitor of apoptosis protein family.

WB, IP

Human

Synthetic peptide mapping to the N-terminus adjacent to Asp330 of human caspase-9.

Rabbit

Polyclonal

Affinity chromatography.

200 µg/ml

Liquid

Supplied in Phosphate Buffered Saline with 50% Glycerol, 0.5% BSA, and 0.02% Thiomersal.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.