Anti-CD18 Antibody [MEM-48] - Low endotoxin, Azide free (A86023)

Anti-CD18 Antibody [MEM-48] - Low endotoxin, Azide free

Mouse monoclonal [MEM-48] antibody to CD18.

This antibody recognizes an extracellular epitope involving residues 534-546 in cysteine-rich repeat 3 of the CD18 antigen. CD18 is a 90-95 kDa type I transmembrane protein expressed on all leukocytes.

Flow Cytometry, IP, WB, IHC-P, IHC-Fr, Functional Studies

FUNC: This antibody induces high-affinity conformation of LFA-1 complex, WB: 2 µg/ml; Positive Control: Kg-1a human leukemia cell lysate, Non-reducing conditions, Flow Cytometry: 2 µg/ml, IHC-P: 10 µg/ml; Positive Control: spleen, microglia.

Human

This antibody does not cross react with Dog.

Leukocytes from a patient suffering from a LGL Type leukemia.

Mouse

Monoclonal

MEM-48

IgG1

Purified by differential precipitation and solid-phase chromatography.

1 mg/ml

90-95 kDa

Liquid

Supplied in Phosphate Buffered Saline, pH 7.4, without Sodium Azide (0.2 µm filter sterilized). Endotoxin level is less than 0.01 EU/µg of the protein.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze/thaw cycles.

Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta, Complement receptor C3 subunit beta, Integrin beta-2, ITGB2, MFI7