Recombinant Anti-CD1a Antibody [rC1A/8110] - BSA and Azide free (A315989)

Anti-CD1a Antibody [rC1A/8110] - BSA and Azide free

Recombinant mouse monoclonal [rC1A/8110] antibody to CD1a.

At least five CD1 genes (CD1a, b, c, d, and e) are identified. CD1 proteins have been demonstrated to restrict T cell response to non-peptide lipid and glycolipid antigens and play a role in non-classical antigen presentation. CD1a is a non-polymorphic MHC Class 1 related cell surface glycoprotein, expressed in association with Beta-2 microglobulin. Anti-CD1a labels Langerhans cell histiocytosis (Histiocytosis X), extranodal histiocytic sarcoma, a subset of T-lymphoblastic lymphoma/leukemia, and interdigitating dendritic cell sarcoma of the lymph node.

Paracortex in a tonsil or a reactive lymph node.

IHC: 1-2 µg/ml

Human

Recombinant full-length human CD1a protein.

Mouse

Monoclonal

rC1A/8110

IgG1

Protein A/G chromatography.

1 mg/ml

49 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

hTa1 thymocyte antigen, T-cell surface antigen T6/Leu-6, T-cell surface glycoprotein CD1a