Anti-CD26 Antibody [202.36] - BSA and Azide free (A251533)

Anti-CD26 Antibody [202.36] - BSA and Azide free

Mouse monoclonal [202.36] antibody to CD26.

This antibody recognizes a glycoprotein of 110kDa, identified as CD26 (Workshop VI; Code: N-L039). It is an atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells and is upregulated during T-cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T-cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection. Cross-linking of CD26 using this antibody dramatically enhances the anti-CD3-induced IL-2 production. In Western blotting, this MAb reacts with only glycosylated CD26, but not with the deglycosylated form. It does not prevent ADA binding to CD26.

Flow Cytometry, IF, IHC

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, IHC: 1-2 µg/ml

Human, Rat

This antibody does not cross react with Porcine or Sheep.

Human T cell clone.

Mouse

Monoclonal

202.36

IgG2b

Protein A/G chromatography.

1 mg/ml

110 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-CD26 Antibody [202.36] (A248351).

ADABP, ADCP-2, ADCP2, Adenosine deaminase complexing protein 2, Dipeptidyl peptidase 4, Dipeptidyl peptidase IV, DPP IV, DPP4, T-cell activation antigen CD26, TP103