This antibody recognises the human CD39 cell surface antigen, a ~70-100 kDa molecule expressed on peripheral blood B cells, T cells and monocytes, and weakly expressed by granulocytes.CD39 has intrinsic ecto-ATPase activity , and expression can be induced on T cells and increased on B cells, as a late activation antigen. Mouse anti Human CD39, clone A1 has been shown to block MHC independent target cell recognition by hapten-specific CTL.
Applications
Flow Cytometry, IF, Functional Assays
Dilutions
Use 10µl of the suggested working dilution to label 106 cells
Reactivity
Human
Immunogen
PHA activated human lymphocytes.
Host
Mouse
Clonality
Monoclonal
Clone ID
A1
Isotype
IgG1
Conjugate
Unconjugated
Purification
Protein A affinity chromatography of tissue culture supernatant.
Concentration
1 mg/ml
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline.
Storage
Store undiluted at -20°C only. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.
General Notes
Mouse anti Human CD39, clone A1 recognizes the human CD39 cell surface antigen, a ~70-100 kDa molecule expressed on peripheral blood B cells, T cells and monocytes, and weakly expressed by granulocytes.CD39 has intrinsic ecto-ATPase activity (Wang et al. 1996), and expression can be induced on T cells and increased on B cells, as a late activation antigen (Maliszewski et al. 1994).Mouse anti Human CD39, clone A1 has been shown to block MHC independent target cell recognition by hapten-specific CTL (Stockl et al. 2001).
Human monoclonal antibody to CD39 Research grade Anti-Human CD39 [PUR001] biosimilar for ELISA, Flow Cytometry, Functional Studies and in vivo Research.
Human monoclonal antibody to CD39 Research grade Anti-Human CD39 [TTX-030] biosimilar for ELISA, Flow Cytometry, Functional Studies and in vivo Research.
Human monoclonal antibody to CD39 Research grade Anti-Human CD39 [ES002] biosimilar for ELISA, Flow Cytometry, Functional Studies and in vivo Research.
Human monoclonal antibody to CD39 Research grade Anti-Human CD39 [PUR001] biosimilar for ELISA, Flow Cytometry, Functional Studies and in vivo Research.
Human monoclonal antibody to CD39 Research grade Anti-Human CD39 [TTX-030] biosimilar for ELISA, Flow Cytometry, Functional Studies and in vivo Research.
Human monoclonal antibody to CD39 Research grade Anti-Human CD39 [ES002] biosimilar for ELISA, Flow Cytometry, Functional Studies and in vivo Research.