Anti-CD41 + Integrin beta 3 Antibody [11C3] (PE) (A278965)

Anti-CD41 + Integrin beta 3 Antibody [11C3] (PE)

Mouse monoclonal [11C3] antibody to CD41 + Integrin beta 3 (PE).

This antibody recognises chicken integrin CD41/61, also known as GPIIb-IIIa. CD41/61 is a heterodimeric cell surface protein, expressed on chicken thrombocytes and cells of the thrombocyte lineage. Avian thrombocytes are nucleated equivalents of mammalian platelets playing roles in coagulation and phagocytosis. Mouse anti Chicken CD41/61 clone 11C3 is reported to induce thrombocyte activation.

Flow Cytometry: Neat, Use 10µl of the suggested working dilution to label 10⁶ cells in 100µl

Chicken

Peripheral blood leukocytes from white leghorn chicken.

Mouse

Monoclonal

11C3

IgG1

Protein G affinity chromatography of tissue culture supernatant.

Reconstitution dependent.

Lyophilized

Reconstitute with 1 ml of distilled water.

Supplied in Phosphate Buffered Saline with 1% BSA, 5% Sucrose, and 0.09% Sodium Azide.

Lyophilized: Store at 4°C. Reconstituted: Store undiluted at 4°C. Do not freeze! This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.

Mouse anti Chicken CD41/61, clone 11C3 recognizes chicken integrin CD41/61, also known as GPIIb-IIIa. CD41/61 is a heterodimeric cell surface protein, expressed on chicken thrombocytes and cells of the thrombocyte lineage. Avian thrombocytes are nucleated equivalents of mammalian platelets playing roles in coagulation and phagocytosis. Mouse anti Chicken CD41/61 clone 11C3 is reported to induce thrombocyte activation (Lacoste-Eleaume et al. 1994).

This product is for research use only. It is not intended for diagnostic or therapeutic use.