Anti-CD90 / Thy1 Antibody [OX-7] (PE) (A281487)

Anti-CD90 / Thy1 Antibody [OX-7] (PE)

Mouse monoclonal [OX-7] antibody to CD90 / Thy1 (PE).

This antibody recognises rat and CD90, also known as Thy1.1, a GPI-anchored membrane protein containing a single V type Ig-like domain CD90 is expressed on a variety of cell types including thymocytes, neuronal cells, stem cells, immature B cells and connective tissues, CD90 is also expressed in T cells in mice.Since Thy1.1 is a monomorphic determinant in rat but polymorphic in mice, clone MRC OX-7 reacts with Thy1.1 mice e.g. AKR and FVB, but not Thy1.2 mice such as CBA and BALB/c. The affinity of the Fab′ of MRC OX-7 for rat Thy1 is 3 x 109m-1 and for mouse Thy1.1 is 3 x 108m-1(1). Mouse anti rat CD90, clone MRC OX-7 has been demonstrated to promote neurite outgrowths on peripherin-stained sympathetic rat neurons, using fluorescence microscopy. Clone OX-7 has also been reported to induce glomerular nephritis in Wistar rats. This product is routinely tested in flow cytometry on rat thymocytes.

Flow Cytometry: Neat - 1:10, Use 10µl of the suggested working dilution to label 10⁶ cells in 100µl

Rat, Rabbit, Mouse, Guinea Pig

Rat Thy1 antigen.

Mouse

Monoclonal

OX-7

IgG1

Protein A affinity chromatography of tissue culture supernatant.

Reconstitution dependent.

Lyophilized

Reconstitute with 1 ml of distilled water.

Supplied in Phosphate Buffered Saline with 1% BSA, 5% Sucrose, and 0.09% Sodium Azide.

Lyophilized: Store at 4°C. Reconstituted: Store undiluted at 4°C. Do not freeze! This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.

Mouse anti Rat CD90 antibody, clone OX-7 recognizes rat and CD90, also known as Thy1.1, a GPI-anchored membrane protein containing a single V type Ig-like domain CD90 is expressed on a variety of cell types including thymocytes, neuronal cells, stem cells, immature B cells and connective tissues, CD90 is also expressed in T cells in mice. Since Thy1.1 is a monomorphic determinant in rat but polymorphic in mice, clone MRC OX-7 reacts with Thy1.1 mice e.g. AKR and FVB, but not Thy1.2 mice such as CBA and BALB/c. The affinity of the Fab′ of MRC OX-7 for rat Thy1 is 3 x 109m-1 and for mouse Thy1.1 is 3 x 108m-1(1).Mouse anti rat CD90, clone MRC OX-7 has been demonstrated to promote neurite outgrowths on peripherin-stained sympathetic rat neurons, using fluorescence microscopy (Jeng et al. 1998). Clone OX-7 has also been reported to induce glomerular nephritis in Wistar rats (Tamura et al. 1996).This product is routinely tested in flow cytometry on rat thymocytes.

CD7, CD90, CD90 antigen, CDw90, FLJ33325, MGC128895, T25, Theta antigen, Thy 1, Thy 1 cell surface antigen, Thy 1 membrane glycoprotein, Thy 1 T cell antigen, Thy 1.2, Thy-1 antigen, Thy-1 membrane glycoprotein, Thy1, Thy1 antigen, Thy1 T cell antigen, Thy1.1, Thy1.2, THY1_HUMAN, Thymus cell antigen 1, theta

This product is for research use only. It is not intended for diagnostic or therapeutic use.