Mouse monoclonal [MEM-108] antibody to CD98 (FITC).
Specificity
This antibody reacts with CD98, a 125 kDa disulfide-linked heterodimer (80 kDa glycosylated heavy chain + 45 kDa non-glykosylated light chain). CD98 is expressed on T lymphocytes (upon activation) and activated NK cells; it is also present at low levels on B lymphocytes, NK cells, monocytes and platelets.
Applications
Flow Cytometry
Dilutions
Flow Cytometry: The reagent is designed for analysis of human blood cells using 20 µl reagent / 100 µl of whole blood or 106 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
Reactivity
Human
Immunogen
RAJI human Burkitt's lymphoma cell line.
Host
Mouse
Clonality
Monoclonal
Clone ID
MEM-108
Isotype
IgG1
Conjugate
FITC
Excitation: 490nm, Emission: 525nm
Purification
This antibody is conjugated with Fluorescein Isothiocyanate (FITC) under optimum conditions. The conjugate is purified by size-exclusion chromatography; removing unconjugated antibody and free fluorochrome.
Predicted MW
125 kDa
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline, pH 7.4, with 15 mM Sodium Azide.
Storage
Shipped at 4°C. Store in the dark at 2-8°C. Do not freeze!
Synonyms
4F2 cell-surface antigen heavy chain, 4F2 heavy chain antigen, 4F2hc, Amino acid transporter heavy chain SLC3A2, Lymphocyte activation antigen 4F2 large subunit, MDU1, SLC3A2, Solute carrier family 3 member 2
Separation of human monocytes (red-filled) from blood debris (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained with Anti-CD98 Antibody [MEM-108] (FITC) (20 µl reagent / 100 µl of peripheral whole blood).
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Proteins predicted to interact with CD98
Predicted protein interactions based upon String database. Revelancy score correlates with probability of interaction.