Anti-CSF-1-R Antibody [ROS-AV170] (A281700)

Anti-CSF-1-R Antibody [ROS-AV170]

Mouse monoclonal [ROS-AV170] antibody to CSF-1-R.

This antibody recognises the chicken homologue of human CSF1R, also known as CD115, CSF-1R, M-CSF receptor and c-fms. CSF1R is a single pass type 1 transmembrane protein belonging to the type III protein kinase family and is the cell surface receptor for both CSF1 and IL-34. Evidence from comparative sequence analysis across a range of vertebrate species indicates that CSF1 and IL-34 interact with distinct regions of CSF1R. CSF1R cell surface expression appears to be one of the earliest events in macrophage lineage cells. Mouse anti Chicken CSF1R, clone ROS-AV170 is a monoclonal antibody that has been generated to recognize chicken CSF1R. Clone ROS-AV170 has been shown to recognize the CSF1R antigen in some, but not all closely related avian species. Mouse anti Chicken CSF1R, clone ROS-AV170 is an excellent marker for chicken macrophages.

Flow Cytometry, IHC-Fr, IF

Flow Cytometry: 1:50 - 1:200, Use 10µl of the suggested working dilution to label 10⁶ cells in 100µl

Chicken, Grey partridge, Guinea Fowl

This antibody does not cross react with Goose, Duck, Quail, Turkey, Mouse, or Rat

Purified ChCSF1R-Fc fusion protein.

Mouse

Monoclonal

ROS-AV170

IgG1

Protein A affinity chromatography of tissue culture supernatant.

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Chicken CSF1R, clone ROS-AV170, recognizes the chicken homologue of human CSF1R, also known as CD115, CSF-1R, M-CSF receptor and c-fms. CSF1R is a single pass type 1 transmembrane protein belonging to the type III protein kinase family and is the cell surface receptor for both CSF1 and IL-34. Evidence from comparative sequence analysis across a range of vertebrate species indicates that CSF1 and IL-34 interact with distinct regions of CSF1R (Garceau et al. 2010).CSF1R cell surface expression appears to be one of the earliest events in macrophage lineage cells (Garceau et al. 2010).Mouse anti Chicken CSF1R, clone ROS-AV170 is a monoclonal antibody that has been generated to recognize chicken CSF1R . Clone ROS-AV170 has been shown to recognize the CSF1R antigen in some, but not all closely related avian species.Mouse anti Chicken CSF1R, clone ROS-AV170 is an excellent marker for chicken macrophages.

CD115, CSF-1 receptor, CSF-1R, EC:2.7.10.1, FMS, M-CSF-R, Macrophage colony-stimulating factor 1 receptor, Proto-oncogene c-Fms