Anti-CSK Antibody (A320194)

Anti-CSK Antibody

Goat polyclonal antibody to CSK.

This antibody recognises an epitope within the C-terminal (CT) region of CSK, also known as c-src tyrosine kinase, Tyrosine-protein kinase CSK, p50CSK or Protein-tyrosine kinase CYL. CSK is a cytoplasmic tyrosine kinase ubiquitously expressed as two mRNA species , which down-regulates the activity of the c-src oncoprotein. CSK is expressed in lung tissues and by macrophages and is highly conserved across species suggesting a role in important regulatory functions (Bräuninger et al. 1992).

WB, IHC-P, ELISA

ELISA: >1:32,000, IHC-P: 0.1 µg/ml - 0.3 µg/ml, WB: 0.5 µg/ml - 2 µg/ml

Human, Rat, Mouse

A peptide sequence of EQLEHIKTHELHL corresponding to the C-terminus of CSK (NP_004374.1).

EQLEHIKTHELHL

Goat

Polyclonal

IgG

500 µg/ml

Approximately 50 kDa in Jurkat cell lysates.

Liquid

Supplied in TRIS Buffered Saline with <0.1% Sodium Azide and 0.5% BSA.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Goat anti Human CSK antibody recognizes an epitope within the C-terminal (CT) region of CSK, also known as c-src tyrosine kinase, Tyrosine-protein kinase CSK, p50CSK or Protein-tyrosine kinase CYL. CSK is a cytoplasmic tyrosine kinase ubiquitously expressed as two mRNA species (Partanen et al. 1991), which down-regulates the activity of the c-src oncoprotein (Chong et al. 2005).CSK is expressed in lung tissues and by macrophages and is highly conserved across species suggesting a role in important regulatory functions (Bräuninger et al. 1992).

C-Src kinase, Protein-tyrosine kinase CYL, Tyrosine-protein kinase CSK