This antibody recognises human BCA-1 (B cell attractant chemokine), a 10.1 kDa CXC cytokine designated CXCL13, a potent chemoattractant for B lymphocytes expressed at high levels in the liver and to a lesser extent by lymph nodes, spleen, stomach, appendix and salivary glands.BCA-1 functions as a ligand for Burkitt's lymphoma receptor 1 (BLR-1), a chemokine receptor designated CXCR5, expressed by all mature B lymphocytes.
Applications
WB, ELISA
Dilutions
ELISA: 0.5 µg/ml, WB: 0.1 - 0.2 µg/ml
Reactivity
Human
Immunogen
Recombinant human CXCL13.
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugate
Unconjugated
Concentration
1 mg/ml after reconstitution.
Product Form
Lyophilized
Reconstitution
Reconstitute with 0.1 ml of distilled water. For long term storage the addition of 0.09% sodium azide is recommended.
Formulation
Supplied in Phosphate Buffered Saline.
Storage
Lyophilized: Store at -20°C. Reconstituted: Store undiluted at -20°C, avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.
General Notes
Rabbit anti Human CXCL13 antibody recognizes human BCA-1 (B cell attractant chemokine), a 10.1 kDa CXC cytokine designated CXCL13, a potent chemoattractant for B lymphocytes expressed at high levels in the liver and to a lesser extent by lymph nodes, spleen, stomach, appendix and salivary glands.BCA-1 functions as a ligand for Burkitt's lymphoma receptor 1 (BLR-1), a chemokine receptor designated CXCR5, expressed by all mature B lymphocytes.