Specificity
This antibody recognises human CXCL5, otherwise known as ENA-78, (epithelial-derived neutrophil-activating protein 78), a CXC chemokine expressed by monocytes, mast cells, platelets, eosinophils and endothelial cells, which acts as a key modulator of the inflammatory response, but also exhibits angiogenic properties, including tumor progression.CXCL5 signals through binding to CXC receptor 2 (CXCR2) and occurs naturally in three isoforms: ENA 5-78 (74 amino acids), ENA 9-78 (70 amino acids) and ENA 10-78 (69 amino acids).