Anti-Cytomegalovirus gB Late Cytoplasmic Antigen Antibody [hCMV34] (A280580)

Anti-Cytomegalovirus gB Late Cytoplasmic Antigen Antibody [hCMV34]

Mouse monoclonal [hCMV34] antibody to Cytomegalovirus gB Late Cytoplasmic Antigen.

This antibody recognises cytomegalovirus glycoprotein B late cytoplasmic antigen. Cytomegalovirus is an enveloped double stranded DNA virus which in humans (HCMV) is commonly known as human herpesvirus 5 (HHV-5). Glycoprotein B (gB) is the main antigenic protein within the envelope of HCMV. It is required for HCMV mediated membrane fusion along with the gH / gL complex. The unprocessed precursor of HCMV gB is 906 amino acids in length, with a MW of approximately 100kDa. Mouse anti Cytomegalovirus gB Late Cytoplasmic Antigen antibody, clone hCMV34 does not react with HSV, VZV or EBV. Reacts with MRC-5 infected cells, but not uninfected cells. Mouse anti Cytomegalovirus gB Late Cytoplasmic Antigen antibody, clone hCMV34 has been used successfully to demonstrate presence of CMV in infected cells by immunofluorescence on paraformaldehyde fixed cell cultures (González-Sánchez et al 2015).

ELISA, IHC-Fr, IF

IF: 0.02 µg/slide - 1 µg/slide

Viral

Native cytomeglaovirus extracts from infected human cells.

Mouse

Monoclonal

hCMV34

IgG2a

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Cytomegalovirus gB Late Cytoplasmic Antigen antibody, clone hCMV34 detects cytomegalovirus glycoprotein B late cytoplasmic antigen. Cytomegalovirus is an enveloped double stranded DNA virus which in humans (HCMV) is commonly known as human herpesvirus 5 (HHV-5). Glycoprotein B (gB) is the main antigenic protein within the envelope of HCMV. It is required for HCMV mediated membrane fusion along with the gH / gL complex. The unprocessed precursor of HCMV gB is 906 amino acids in length, with a MW of approximately 100kDa. Mouse anti Cytomegalovirus gB Late Cytoplasmic Antigen antibody, clone hCMV34 does not react with HSV, VZV or EBV. Reacts with MRC-5 infected cells, but not uninfected cells.Mouse anti Cytomegalovirus gB Late Cytoplasmic Antigen antibody, clone hCMV34 has been used successfully to demonstrate presence of CMV in infected cells by immunofluorescence on paraformaldehyde fixed cell cultures (González-Sánchez et al 2015).