This antibody recognises defender of apoptotic cell death 1 (DAD1). DAD1 was discovered as a negative regulator of programmed cell death, and has since been identified as a subunit of the mammalian oligosaccharyltransferase complex (OCT). DAD1 is required for the function and structural integrity of the OCT.
Applications
WB
Dilutions
WB: 0.5 µg/ml - 2 µg/ml
Reactivity
Human, Mouse
Immunogen
Synthetic peptide corresponding to 14 amino acids within the C-terminus of human DAD1.
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugate
Unconjugated
Concentration
1 mg/ml
Molecular Weight
Approximately 22 kDa in HepG2 cell lysates.
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 0.02% Sodium Azide.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
General Notes
Rabbit antiuman DAD1 antibody recognizes defender of apoptotic cell death 1 (DAD1). DAD1 was discovered as a negative regulator of programmed cell death, and has since been identified as a subunit of the mammalian oligosaccharyltransferase complex (OCT). DAD1 is required for the function and structural integrity of the OCT.
Synonyms
DAD-1, Defender against cell death 1, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1, Oligosaccharyl transferase subunit DAD1
