Anti-DAZL Antibody [DAZL/4253] - BSA and Azide free
Description
Mouse monoclonal [DAZL/4253] antibody to DAZL.
Specificity
Specific for human DAZL, a member of the DAZ (deleted in azoospermia) family of RNA binding proteins. DAZL is expressed in fetal and adult testes and ovaries, and is believed to play a role in germ cell development. In adult germ cells, the expression of DAZL is localized to the cytoplasm. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. Clone DAZL/4253 recognizes DAZL at its C terminus, and is used in detection of DAZL expression by various methods.
Applications
IF, WB, IHC-P
Dilutions
IF: 1-2 µg/ml, WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml
Reactivity
Human, Mouse, Rat, Cynomolgus Monkey
Immunogen
C terminal DAZL protein.
Sequence
CRVHHFRRSRAMLKSV
Host
Mouse
Clonality
Monoclonal
Clone ID
DAZL/4253
Isotype
IgG1
Conjugate
Unconjugated
Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Molecular Weight
33 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
SDS-PAGE analysis of Anti-DAZL Antibody [DAZL/4253] under non-reduced and reduced conditions; showing intact IgG and intact heavy and light chains, respectively. SDS-PAGE analysis confirms the integrity and purity of the antibody.
Immunohistochemical analysis of formalin-fixed, paraffin-embedded human testis using Anti-DAZL Antibody [DAZL/4253].
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