Anti-Dehydroepiandrosterone Antibody [DHEA(-3):1-19.1 (BGN/117/1191)] (A280254)

Anti-Dehydroepiandrosterone Antibody [DHEA(-3):1-19.1 (BGN/117/1191)]

Mouse monoclonal [DHEA(-3):1-19.1 (BGN/117/1191)] antibody to Dehydroepiandrosterone.

This antibody recognises dehydroepiandrosterone (DHEA) a steroid prohormone which is the precursor of all sex steroids. DHEA is produced primarily by the adrenal glands, and together with its ester DHEA-sulphate (DHEAS), has been implicated in a wide range of physiological roles including aging, immunology, memory and obesity. In particular, DHEA and DHEAS differentially regulate growth-factor induced proliferation of chromaffin cells, and are thought to affect neurogenesis, neuronal survival, and neuronal stem cell proliferation. Blood measurements of DHEAS/DHEA are useful to detect excess adrenal activity due to adrenal cancer or hyperplasia, including certain forms of congenital adrenal hyperplasia.

ELISA: 1:1,000 - 1:10,000

Species Independent

DHEA-3-HS-BSA conjugate.

Mouse

Monoclonal

DHEA(-3):1-19.1 (BGN/117/1191)

IgG1

Protein A affinity chromatography of tissue culture supernatant.

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Dehydroepiandrosterone antibody, clone DHEA(-3):1-19.1 detects dehydroepiandrosterone (DHEA) a steroid prohormone which is the precursor of all sex steroids. DHEA is produced primarily by the adrenal glands, and together with its ester DHEA-sulphate (DHEAS), has been implicated in a wide range of physiological roles including aging, immunology, memory and obesity. In particular, DHEA and DHEAS differentially regulate growth-factor induced proliferation of chromaffin cells, and are thought to affect neurogenesis, neuronal survival, and neuronal stem cell proliferation. Blood measurements of DHEAS/DHEA are useful to detect excess adrenal activity due to adrenal cancer or hyperplasia, including certain forms of congenital adrenal hyperplasia.