Recombinant Anti-Desmoglein 3 / PVA Antibody [DSG3/8252R] (A314891)

Anti-Desmoglein 3 / PVA Antibody [DSG3/8252R]

Recombinant rabbit monoclonal [DSG3/8252R] antibody to Desmoglein 3 / PVA.

Recognizes a protein of 130kDa, identified as Desmoglein-3 (DSG3). This MAb is highly specific to Desmoglein-3 and does not cross-react with other members of the Desmoglein-family. DSG3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Currently, three desmoglein subfamily members are identified and all are members of the cadherin cell adhesion molecule superfamily.

A431 cells. Lung squamous cell carcinoma.

IHC: 1-2 µg/ml

Human

Recombinant fragment (around Amino Acids 300-500) of human DSG3 protein. The exact sequence is proprietary.

Rabbit

Monoclonal

DSG3/8252R

kappa

Protein A/G chromatography.

200 µg/ml

130 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.