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Anti-DR3 / LARD Antibody (A283851)

This product is discontinued

Anti-DR3 / LARD Antibody (A283851) has been discontinued and is no longer available.

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Name
Anti-DR3 / LARD Antibody
Description
Rabbit polyclonal antibody to DR3 / LARD.
Specificity
This antibody recognises a ~59 kDa apoptosis related protein designated DR3 (death receptor-3).DR3 is a cell surface receptor with a death domain, with functional similarities to TNFR1 and Fas (CD95).The ligand for DR3 has very recently been identified and has been termed Apo-3L. DR3 itself has also been called Wsl-1, Apo-3, TRAMP and LARD, and functionally induces apoptosis and NF-?B activation.
Applications
WB
Dilutions
WB: 1:500 - 1:1,000
Reactivity
Human
Immunogen
A peptide sequence of QGGTRSPRCDCAGDFH from amino terminus of human DR3.
Sequence
QGGTRSPRCDCAGDFH
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugate

Unconjugated

Concentration
1 mg/ml
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 0.02% Sodium Azide.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
General Notes
Rabbit anti Human DR3 antibody recognises a ~59 kDa apoptosis related protein designated DR3 (death receptor-3).DR3 is a cell surface receptor with a death domain, with functional similarities to TNFR1 and Fas (CD95).The ligand for DR3 has very recently been identified and has been termed Apo-3L. DR3 itself has also been called Wsl-1, Apo-3, TRAMP and LARD, and functionally induces apoptosis and NF-?B activation.
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.