General Notes
Rabbit anti Human DR3 recognizes death receptor 3. DR3 is a cell surface receptor containing a death domain, with functional similarities to TNFR1 and Fas/CD95 (Chinnaiyan et al. 1996). The receptor for DR3 is also known as Apo-3L (Marsters et al. 1998), Wsl-1, Apo-3, TRAMP and LARD. DR3 is an inducer of apoptosis and NF-KB activation (Sheikh and Huang 2003).