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Anti-DR3 / LARD Antibody (A283852)

This product is discontinued

Anti-DR3 / LARD Antibody (A283852) has been discontinued and is no longer available.

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Name
Anti-DR3 / LARD Antibody
Description
Rabbit polyclonal antibody to DR3 / LARD.
Specificity
This antibody recognises death receptor 3. DR3 is a cell surface receptor containing a death domain, with functional similarities to TNFR1 and Fas/CD95. The receptor for DR3 is also known as Apo-3L , Wsl-1, Apo-3, TRAMP and LARD. DR3 is an inducer of apoptosis and NF-KB activation.
Applications
WB, IHC-Fr
Dilutions
WB: 1.0 - 5.0 µg/ml
Reactivity
Human, Mouse
Immunogen
A peptide corresponding to the extracellular domain of human DR3.
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugate

Unconjugated

Concentration
1 mg/ml
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 0.02% Sodium Azide.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
General Notes
Rabbit anti Human DR3 recognizes death receptor 3. DR3 is a cell surface receptor containing a death domain, with functional similarities to TNFR1 and Fas/CD95 (Chinnaiyan et al. 1996). The receptor for DR3 is also known as Apo-3L (Marsters et al. 1998), Wsl-1, Apo-3, TRAMP and LARD. DR3 is an inducer of apoptosis and NF-KB activation (Sheikh and Huang 2003).
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.