Anti-DR5 Antibody [DR5-01-1] (APC) (A121839)

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$210

Mouse monoclonal [DR5-01-1] antibody to DR5 (APC) for Flow Cytometry.

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Alternative Formats and ConjugatesAlternative Formats

FITC PE Unconjugated

Shipping Information

Freight/Packing Charges: $40

Dispatched from St. Louis, MO.

Lead Time: 5-8 business days.

Specifications

Name

Anti-DR5 Antibody [DR5-01-1] (APC)

Description

Mouse monoclonal [DR5-01-1] antibody to DR5 (APC).

Specificity

The antibody recognizes an extracellular domain of TRAIL-R2 (DR5). TRAIL-R2 is one of two TNF superfamily member intracellular death domain containing receptors for TRAIL (APO2L).

Applications

Flow Cytometry

Dilutions

Flow Cytometry: 1-5 µg/ml; Positive Control: JURKAT human peripheral blood leukemia T cell line.

Reactivity

Human

Immunogen

Recombinant fusion protein of human IgG heavy chain and extracellular domain of DR5.

Host

Mouse

Clonality

Monoclonal

Clone ID

DR5-01-1

Isotype

IgG1

Conjugate

APC

Excitation: 645nm, Emission: 660nm

Purification

This antibody is conjugated with Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography; removing unconjugated antibody and free fluorochrome.

Concentration

100 µg/ml

Product Form

Liquid

Formulation

Supplied in Phosphate Buffered Saline, pH 7.4, with 15 mM Sodium Azide.

Storage

Shipped at 4°C. Store in the dark at 2-8°C. Do not freeze!

Synonyms

CD262, Death receptor 5, KILLER, TNF-related apoptosis-inducing ligand receptor 2, TNFRSF10B, TRAIL receptor 2, TRAIL-R2, TRAILR2, TRICK2, Tumor necrosis factor receptor superfamily member 10B, ZTNFR9

Isotype Controls

Mouse IgG1 [MOPC-21] (APC) (A86198)

Disclaimer

This product is for research use only. It is not intended for diagnostic or therapeutic use.

Scientific Validation DataValidation Data (1)

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Flow Cytometry - Anti-DR5 Antibody [DR5-01-1] (APC) (A121839)

Separation of TRAIL-R2 transfected HEK-293 stained with Anti-DR5 Antibody [DR5-01-1] (APC) (A121839), (concentration in sample 1,7 µg/ml, red-filled) from TRAIL-R2 transfected HEK-293 stained using Mouse IgG1 kappa Isotype Control [MOPC-21] (APC) (A86198), (concentration in sample 1,7 µg/ml, same as CD262 APC concentration, black-dashed) in flow cytometry analysis (surface staining) of TRAIL-R2 transfected HEK-293 suspension.

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