Anti-DRAM Antibody (A283182)

Anti-DRAM Antibody

Rabbit polyclonal antibody to DRAM.

This antibody recognises human DRAM, a lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. DRAM is significantly down-regulated in tumor cell lines by methylation-dependent transcriptional silencing.

WB, IHC-P

IHC-P 1: 2.5 µg/ml, WB: 0.5 - 1 µg/ml

Human, Mouse, Rat

A peptide corresponding to 16 amino acids near the C-terminus of human DRAM.

Rabbit

Polyclonal

IgG

Approximately 16 and 31 kDa in 293 cell lysate

Liquid

Supplied in Phosphate Buffered Saline with 0.02% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Rabbit anti DRAM (C-terminal) antibody recognizes human DRAM, a lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. DRAM is significantly down-regulated in tumor cell lines by methylation-dependent transcriptional silencing.

Damage-regulated autophagy modulator, DNA damage-regulated autophagy modulator protein 1, DRAM1