Anti-Dynamin (phospho Ser774) Antibody (A283953)

Anti-Dynamin (phospho Ser774) Antibody

Sheep polyclonal antibody to Dynamin (phospho Ser774).

This antibody recognises dynamin, also known as B-dynamin and D100, when phosphorylated at serine 774.Dynamin is a phosphoprotein expressed at nerve terminals, which plays an important role in the regulation of synaptic vesicle endocytosis. Cyclin dependent protein kinase 5 (cdk5) has been shown to phosphorylate serine 774 and 778 in vivo. Dephosphorylation of these residues is essential for endocytosis of synaptic vesicles.

WB, IHC-Fr, IF

WB: 1:1,000

Rat, Human, Monkey, Bovine, Chicken, Mouse, Dog

Synthetic phosphopeptide corresponding to an amino acid sequence within dynamin which includes phosphorylated Ser774.

Sheep

Polyclonal

IgG

Lot Specific

Approximately 95 kDa in rat hippocampus lysates.

Liquid

Supplied in 10mM HEPES, pH 7.5, with 0.01% BSA, 50% Glycerol, and 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Sheep anti Rat dynamin (pSer774) antibody recognizes dynamin, also known as B-dynamin and D100, when phosphorylated at serine 774.Dynamin is a phosphoprotein expressed at nerve terminals, which plays an important role in the regulation of synaptic vesicle endocytosis. Cyclin dependent protein kinase 5 (cdk5) has been shown to phosphorylate serine 774 and 778 in vivo. Dephosphorylation of these residues is essential for endocytosis of synaptic vesicles.

DNM, DNM1, Dynamin I, Dynamin-1